COX6B2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60483
Background:
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.
Alternative Name:
Cytochrome c oxidase subunit 6B2, Cancer/testis antigen 59, CT59, Cytochrome c oxidase subunit VIb isoform 2, COX VIb-2, Cytochrome c oxidase subunit VIb, testis-specific isoform, COX6B2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: COX6B2 polyclonal antibody detects endogenous levels of COX6B2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human COX6B2.
MW: ~ 11 kDa
Swis Prot.: Q6YFQ2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 97% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.5.
Storage:
Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.
Alternative Name:
Cytochrome c oxidase subunit 6B2, Cancer/testis antigen 59, CT59, Cytochrome c oxidase subunit VIb isoform 2, COX VIb-2, Cytochrome c oxidase subunit VIb, testis-specific isoform, COX6B2
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: COX6B2 polyclonal antibody detects endogenous levels of COX6B2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human COX6B2.
MW: ~ 11 kDa
Swis Prot.: Q6YFQ2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 97% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.5.
Storage:
Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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