COX6C Polyclonal Antibody

Background:
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
COX 6C, Cox6c, COX6C, Cytochrome c oxidase polypeptide VIc, Cytochrome c oxidase subunit 6C, cytochrome c oxidase subunit VIc, Cytochrome c oxidase subunit VIc preprotein

Immunogen: Synthetic peptide of human COX6C

Swissprot: P09669
Gene Accession: NP004365

Calculated MW: 9 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.