COX7B Polyclonal Antibody

Background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
COX7B, COX7B, Cytochrome c oxidase chain VIIb, Cytochrome c oxidase polypeptide VIIb, Cytochrome c oxidase subunit 7B, Cytochrome c oxidase subunit 7B mitochondrial, Cytochrome c oxidase subunit VIIb, mitochondrial

Immunogen: Recombinant protein of human COX7B

Swissprot: P24311
Gene Accession: BC018386

Calculated MW: 9 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-109528