CP110 polyclonal, anti-human

Background:
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.

Synonyms: Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human CP110

Gene Symbol: CP110

Gene ID: 9738

Swiss prot: O43303

Calculated MW: 113kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.