CREB polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10263-100
Catalog Number: AC-ABV10263-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB
Datasheet
Request Information
Background:
Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Other Names:
CREB-1, cAMP-response Element-binding Protein-1, CREB1 , CREB, MGC9284
Primary Accession: P15337
Gene Name: Creb1
Gene ID: 81646
Concentration (mg/ml): 0.5 mg/ml
Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Other Names:
CREB-1, cAMP-response Element-binding Protein-1, CREB1 , CREB, MGC9284
Primary Accession: P15337
Gene Name: Creb1
Gene ID: 81646
Concentration (mg/ml): 0.5 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review