CREB3 Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20041a
Background:
This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-response element and regulates cellproliferation. The protein interacts with host cell factor C1,which also associates with the herpes simplex virus (HSV) proteinVP16 that induces transcription of HSV immediate-early genes. Thisprotein and VP16 both bind to the same site on host cell factor C1.It is thought that the interaction between this protein and hostcell factor C1 plays a role in the establishment of latency duringHSV infection. This protein also plays a role in leukocytemigration, tumor suppression, and endoplasmic reticulumstress-associated protein degradation. Additional transcriptvariants have been identified, but their biological validity hasnot been determined.
Other Names:
Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP
Target/Specificity:
The synthetic peptide sequence is selected from aa 81-94 of HUMAN CREB3
Gene Name: CREB3
Gene ID: 10488
Primary Accession: O43889
Other Accession: NP_006359.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-response element and regulates cellproliferation. The protein interacts with host cell factor C1,which also associates with the herpes simplex virus (HSV) proteinVP16 that induces transcription of HSV immediate-early genes. Thisprotein and VP16 both bind to the same site on host cell factor C1.It is thought that the interaction between this protein and hostcell factor C1 plays a role in the establishment of latency duringHSV infection. This protein also plays a role in leukocytemigration, tumor suppression, and endoplasmic reticulumstress-associated protein degradation. Additional transcriptvariants have been identified, but their biological validity hasnot been determined.
Other Names:
Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP
Target/Specificity:
The synthetic peptide sequence is selected from aa 81-94 of HUMAN CREB3
Gene Name: CREB3
Gene ID: 10488
Primary Accession: O43889
Other Accession: NP_006359.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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