CREBBP Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP1077b
Background:
CREBBP is an acetyltransferase enzyme that acetylates histones, giving a specific tag for transcriptional activation. This enzyme also acetylates non-histone proteins, like NCOA3 coactivator. CREBBP mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein, and as a coactivator, augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes.
Other Names:
CREB-binding protein, CREBBP, CBP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1077b was selected from the Center region of human CREBBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CREBBP (HGNC:2348)
Gene ID: 1387
Primary Accession: Q92793
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CREBBP is an acetyltransferase enzyme that acetylates histones, giving a specific tag for transcriptional activation. This enzyme also acetylates non-histone proteins, like NCOA3 coactivator. CREBBP mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein, and as a coactivator, augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes.
Other Names:
CREB-binding protein, CREBBP, CBP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1077b was selected from the Center region of human CREBBP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CREBBP (HGNC:2348)
Gene ID: 1387
Primary Accession: Q92793
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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