CRH polyclonal (C-term), anti-human
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In stock
SKU
AC-AP11244b
Catalog Number: AC-AP11244b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23963
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23963
Applications: WB
Datasheet
Request Information
Background:
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Other Names:
Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone, CRH
Target/Specificity:
This CRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-156 amino acids from the C-terminal region of human CRH.
Antigen Region:
129-156
Antigen Type: Synthetic Peptide
Gene Name: CRH
Gene ID: 1392
Primary Accession: P06850
NCBI Accession: NP_000747.1
Other Accession: NP_000747.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Other Names:
Corticoliberin, Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone, CRH
Target/Specificity:
This CRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-156 amino acids from the C-terminal region of human CRH.
Antigen Region:
129-156
Antigen Type: Synthetic Peptide
Gene Name: CRH
Gene ID: 1392
Primary Accession: P06850
NCBI Accession: NP_000747.1
Other Accession: NP_000747.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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