CRHR2 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms: CRF2R, CRH2R, CRF-RB, CRF2, CRFR2, HM-CRF

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CRHR2

Gene Symbol: CRHR2

Gene ID: 1395

Swiss prot: Q13324

Calculated MW: 45kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.