CRHR2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Area: Neuroscience

Synonyms:
Corticotropin releasing hormone receptor 2, Corticotropin-releasing factor receptor 2, Corticotropin-releasing hormone receptor 2, CRF 2, CRF 2R, CRF R2, CRF RB, CRF-R-2, CRF-R2, CRF2, CRF2 receptor beta isoform, CRF2R, CRFR 2, CRFR-2, CRFR2, CRFR2, CRH 2R, CRH R2, CRH-R-2, CRH-R2, CRH2R, CRHR 2, Crhr2, HM CRF

Immunogen: Synthetic peptide of human CRHR2

Swissprot: Q13324
Gene Accession: NP_001189404

Calculated MW: 48 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20550/sc-20549/sc-1826