CRIM1 antibody (clone 60000), anti-human
€435.00
In stock
SKU
AC-AT1623a
Catalog Number: AC-AT1623a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1623a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1623a">Request Information
Background:
Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and is mediated, at least in part, by the concentration of ventrally expressed Sonic hedgehog protein (SHH; MIM 600725). Dorsally expressed factors, such as members of the bone morphogenic protein (e.g., BMP4; MIM 112262) and transforming growth factor-beta (e.g., TGFB1; MIM 190180) families, can repress the induction of these neurons. CRIM1 may interact with growth factors implicated in motor neuron differentiation and survival (Kolle et al., 2000 [PubMed 10642437]).
Other Names:
Cysteine-rich motor neuron 1 protein, CRIM-1, Cysteine-rich repeat-containing protein S52, Processed cysteine-rich motor neuron 1 protein, CRIM1, S52
Antigen Type:
Recombinant Protein
Gene Name: CRIM1
Gene ID: 51232
NCBI Accession: NP_057525.1
Primary Accession: Q9NZV1
Other Accession: NM_016441
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Motor neurons are among the earliest neurons to appear after the commencement of cell patterning and the beginning of cell differentiation. Differentiation occurs in a ventral-to-dorsal gradient and is mediated, at least in part, by the concentration of ventrally expressed Sonic hedgehog protein (SHH; MIM 600725). Dorsally expressed factors, such as members of the bone morphogenic protein (e.g., BMP4; MIM 112262) and transforming growth factor-beta (e.g., TGFB1; MIM 190180) families, can repress the induction of these neurons. CRIM1 may interact with growth factors implicated in motor neuron differentiation and survival (Kolle et al., 2000 [PubMed 10642437]).
Other Names:
Cysteine-rich motor neuron 1 protein, CRIM-1, Cysteine-rich repeat-containing protein S52, Processed cysteine-rich motor neuron 1 protein, CRIM1, S52
Antigen Type:
Recombinant Protein
Gene Name: CRIM1
Gene ID: 51232
NCBI Accession: NP_057525.1
Primary Accession: Q9NZV1
Other Accession: NM_016441
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review