CRIM1(CT) polyclonal, anti- antibody

Background:
CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

Other Names:
Cysteine rich transmembrane BMP regulator 1 (chordin-like), CRIM-1, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52

Primary Accession: Q9NZV1

Gene Name: CRIM1

Gene ID: 51232

Concentration (mg/ml): 1 mg/ml