CRIPTO (TDGF1) Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP2047a
Background:
TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.
Other Names:
Teratocarcinoma-derived growth factor 1, Cripto-1 growth factor, CRGF, Epidermal growth factor-like cripto protein CR1, TDGF1, CRIPTO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2047a was selected from the N-term region of human TDGF1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CRIPTO {ECO:0000303|PubMed:2792079, ECO:0000312|HGNC:HGNC:11701}
Gene ID: 6997
Primary Accession: P13385
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.
Other Names:
Teratocarcinoma-derived growth factor 1, Cripto-1 growth factor, CRGF, Epidermal growth factor-like cripto protein CR1, TDGF1, CRIPTO
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2047a was selected from the N-term region of human TDGF1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CRIPTO {ECO:0000303|PubMed:2792079, ECO:0000312|HGNC:HGNC:11701}
Gene ID: 6997
Primary Accession: P13385
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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