CRK (clone 3H7) mouse monoclonal, anti-human

CRK (clone 3H7) mouse monoclonal, anti-human

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In stock
SKU
EKL-AMM03483
Catalog Number: EKL-AMM03483
Size(s): 50 μl, 100 μl, 500 μl
Isotype: Mouse IgG2b
Applications: WB
Datasheet
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Backgroud: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Synonyms: Adapter molecule crk, avian sarcoma virus CT10 (v-crk) oncogene homolog, CRK, CRKII, Proto-oncogene c-Crk

Gene Name: CRK

Gene ID: 1398

SwissProt ID: P46108

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
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