CRKL polyclonal, anti-human, mouse

Background:
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Synonyms: CRKL, Crk-like protein,

Cellular Location: Endosome Cytosol Nucleus

Immunogen:
A synthetic peptide of human CRKL

Gene Symbol: CRKL

Gene ID: 1399

Swiss prot: P46109

Calculated MW: 34kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.