CRKL Polyclonal Antibody

Background:
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction

Synonyms:
Crk L, Crk like protein, Crk-like protein, Crkl, CRKL, Crkol, HGNC:2363 , Oncogene CrkL, V crk avian sarcoma virus CT10 oncogene homolog like, v crk sarcoma virus CT10 oncogene homolog (avian) like, V crk sarcoma virus CT10 oncogene homolog avian like

Immunogen: Synthetic peptide of human CRKL

Swissprot: P46109
Gene Accession: NP_005198

Calculated MW: 34 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-31693/sc-31694/sc-9005/sc-319