CRMP1 polyclonal, anti-human, mouse, rat

Background:
Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.

Synonyms: DRP1, DRP-1, CRMP-1, DPYSL1, ULIP-3

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CRMP1

Gene Symbol: CRMP1

Gene ID: 1400

Swiss prot: Q14194

Calculated MW: 62kDa

Recommended dilution:
WB 1:500-1000, IHC 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.