CRP Polyclonal Antibody

Background:
C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular,pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination,bacterial capsular swelling,phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Immunology

Synonyms:
Pentraxin 1, short, C reactive protein, C reactive protein pentraxin related, C-reactive protein(1-205), CRP, CRP, MGC88244, Pentraxin 1, PTX 1, PTX1

Immunogen: Recombinant Rat C-reactive protein

Swissprot: P48199

Calculated MW: 25 kDa
Observed MW: 30 kDa

Purification Method: Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000 IHC 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.