CRSP7 antibody (clone 2G10), anti-human
€435.00
In stock
SKU
AC-AT1633a
Catalog Number: AC-AT1633a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
Request Information AC-AT1633a">Request Information
Background:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Other Names:
Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70 kDa component, ARC70, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26, Transcriptional coactivator CRSP70, MED26, ARC70, CRSP7
Antigen Type:
Recombinant Protein
Gene Name: MED26
Gene ID: 9441
NCBI Accession: NP_004822.2
Primary Accession: O95402
Other Accession: NM_004831
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Other Names:
Mediator of RNA polymerase II transcription subunit 26, Activator-recruited cofactor 70 kDa component, ARC70, Cofactor required for Sp1 transcriptional activation subunit 7, CRSP complex subunit 7, Mediator complex subunit 26, Transcriptional coactivator CRSP70, MED26, ARC70, CRSP7
Antigen Type:
Recombinant Protein
Gene Name: MED26
Gene ID: 9441
NCBI Accession: NP_004822.2
Primary Accession: O95402
Other Accession: NM_004831
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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