CRSP8 antibody (clone 8B8), anti-human
€435.00
In stock
SKU
AC-AT1634a
Catalog Number: AC-AT1634a
Size: 50 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 50 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT1634a">Request Information
Background:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Other Names:
Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27, P37 TRAP/SMCC/PC2 subunit, Transcriptional coactivator CRSP34, MED27, CRSP34 {ECO:0000312|EMBL:AAD127211}, CRSP8
Antigen Type:
Recombinant Protein
Gene Name: MED27
Gene ID: 9442
NCBI Accession: NP_001240810.1;NP_004260.2
Primary Accession: Q6P2C8
Other Accession: BC002878
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Other Names:
Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8, CRSP complex subunit 8, Mediator complex subunit 27, P37 TRAP/SMCC/PC2 subunit, Transcriptional coactivator CRSP34, MED27, CRSP34 {ECO:0000312|EMBL:AAD127211}, CRSP8
Antigen Type:
Recombinant Protein
Gene Name: MED27
Gene ID: 9442
NCBI Accession: NP_001240810.1;NP_004260.2
Primary Accession: Q6P2C8
Other Accession: BC002878
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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