CRTAM Polyclonal Antibody

Background:
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Research Area: Immunology

Synonyms:
CD355, Class I MHC restricted T cell associated molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM, CRTAM, Cytotoxic and regulatory T cell molecule, Cytotoxic and regulatory T-cell molecule

Immunogen: Recombinant protein of human CRTAM

Swissprot: O95727
Gene Accession: BC070266

Calculated MW: 45 kDa
Observed MW: Refer to Figures

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-46881/sc-46882/sc-46883/sc-46879/sc-99228/sc-99202