CRTC2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP14167b
Catalog Number: AC-AP14167b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18081
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18081
Applications: WB
Datasheet
Request Information
Background:
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Other Names:
CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2, CRTC2, TORC2
Target/Specificity:
This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 664-693 amino acids from the C-terminal region of human CRTC2.
Antigen Region:
664-693
Antigen Type: Synthetic Peptide
Gene Name: CRTC2
Gene ID: 200186
Primary Accession: Q53ET0
NCBI Accession: NP_859066.1
Other Accession: NP_859066.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Other Names:
CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2, CRTC2, TORC2
Target/Specificity:
This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 664-693 amino acids from the C-terminal region of human CRTC2.
Antigen Region:
664-693
Antigen Type: Synthetic Peptide
Gene Name: CRTC2
Gene ID: 200186
Primary Accession: Q53ET0
NCBI Accession: NP_859066.1
Other Accession: NP_859066.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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