CRY1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8561
Background:
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
Alternative Name:
Cryptochrome-1, CRY1, PHLL1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CRY1 polyclonal antibody detects endogenous levels of CRY1 protein.
Immunogen:
Recombinant full length Human CRY1.
MW: ~ 66kDa
Swis Prot.: Q16526
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
Alternative Name:
Cryptochrome-1, CRY1, PHLL1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CRY1 polyclonal antibody detects endogenous levels of CRY1 protein.
Immunogen:
Recombinant full length Human CRY1.
MW: ~ 66kDa
Swis Prot.: Q16526
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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