CRYM antibody (clone 6B3), anti-human
€435.00
In stock
SKU
AC-AT1645a
Catalog Number: AC-AT1645a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IP, E
Request Information AC-AT1645a">Request Information
Background:
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Other Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Antigen Type:
Recombinant Protein
Gene Name: CRYM
Gene ID: 1428
NCBI Accession: NP_001014444.1;NP_001879.1
Primary Accession: Q14894
Other Accession: NM_001888
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Other Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Antigen Type:
Recombinant Protein
Gene Name: CRYM
Gene ID: 1428
NCBI Accession: NP_001014444.1;NP_001879.1
Primary Accession: Q14894
Other Accession: NM_001888
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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