CRYM Polyclonal Antibody

Background:
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness.

Research Area: Cancer, Neuroscience, Signal transduction

Synonyms:
CRYM, CRYM, Crystallin mu, DFNA 40, DFNA40, Ketimine reductase, Mu crystallin homolog, Mu-crystallin homolog, NADP regulated thyroid hormone binding protein, NADP-regulated thyroid-hormone-binding protein, OTTHUMP00000115878, THBP, Thiomorpholine carboxylate dehydrogenase

Immunogen: Fusion protein of human CRYM

Swissprot: Q14894
Gene Accession: BC018061

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.