CRYM polyclonal (Center), anti-mouse
€0.00
In stock
SKU
AC-AP19781c
Catalog Number: AC-AP19781c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40546
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB40546
Applications: WB
Datasheet
Request Information
Background:
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Other Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Target/Specificity:
This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
Antigen Region:
154-183
Antigen Type: Synthetic Peptide
Gene Name: CRYM
Gene ID: 1428
Primary Accession: Q14894
NCBI Accession: NP_001014444.1;NP_001879.1
Other Accession: NP_001879.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
Other Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Target/Specificity:
This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
Antigen Region:
154-183
Antigen Type: Synthetic Peptide
Gene Name: CRYM
Gene ID: 1428
Primary Accession: Q14894
NCBI Accession: NP_001014444.1;NP_001879.1
Other Accession: NP_001879.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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