Crystallin alpha A/CRYAA (clone c9F2), anti-human

Description
alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency,which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively.alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They actas molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weightaggregates. These heterogeneous aggregates consist of 30-40 subunits of the alpha-A and alpha-B subunitshave a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and theparticipation in the intracellular architecture.Alternative Names
Acry-1, Alpha crystallin A chain, CRYA1, CRYAA, Crystallin alpha 1, Crystallin alpha A, Heat shock protein beta 4, HSPB 4, HspB4, Zonular Central Nuclear CataractConcentration
1mg/ml (determined by BCA assay)Concentration
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerolStorage: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.