CRYZ Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6566a
Background:
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.
Other Names:
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin, CRYZ
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6566a was selected from the N-term region of human CRYZ. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CRYZ
Gene ID: 1429
Primary Accession: Q08257
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.
Other Names:
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin, CRYZ
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6566a was selected from the N-term region of human CRYZ. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CRYZ
Gene ID: 1429
Primary Accession: Q08257
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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