CSE1L antibody (clone 10000), anti-human
€435.00
In stock
SKU
AC-AT1651a
Catalog Number: AC-AT1651a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IF, E
Request Information AC-AT1651a">Request Information
Background:
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Other Names:
Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter, CSE1L, CAS, XPO2
Antigen Type:
Recombinant Protein
Gene Name: CSE1L
Gene ID: 1434
NCBI Accession: NP_001243064.1;NP_001307.2
Primary Accession: P55060
Other Accession: NM_001316
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Other Names:
Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter, CSE1L, CAS, XPO2
Antigen Type:
Recombinant Protein
Gene Name: CSE1L
Gene ID: 1434
NCBI Accession: NP_001243064.1;NP_001307.2
Primary Accession: P55060
Other Accession: NM_001316
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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