CSEN polyclonal, anti-human

Quantity: 100 µg

Background:
KCNIP3, also known as Calsenilin, is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. This gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. KCNIP3 is mapped to 2q11.1. The encoded protein functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. KCNIP3 has been shown to interact with PSEN1 and PSEN2.

Description:
Rabbit IgG polyclonal antibody for Calsenilin (KCNIP3) detection. Tested with WB in Human.

Synonyms:
4933407H12Rik antibody, A type potassium channel modulatory protein 3 antibody, A-type potassium channel modulatory protein 3 antibody, AI413860 antibody, Calsenilin antibody, CSEN antibody,, DRE Antagonist Modulator antibody, DRE-antagonist modulator antibody, DREAM antibody, EF Hand Transcription Factor antibody, KCHIP 3 antibody, KCHIP3 antibody, KCNIP 3 antibody, KCNIP3 antibody, Kv channel interacting protein 3 antibody, Kv channel-interacting protein 3 antibody, MGC18289 antibody, Potassium channel interacting protein 3 antibody, Presenilin Binding Protein antibody, R74849 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human CSEN(1-16aa MQPAKEVTKASDGSLL).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.