CSF1R monoclonal (Ascites), anti-human
€470.00
In stock
SKU
AC-AM1875a
Catalog Number: AC-AM1875a
Size: 100 µl
Isotype: mouse IgG1,IGM,K
Clone Name: 177CT7.1.1
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1,IGM,K
Clone Name: 177CT7.1.1
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq].
Other Names:
Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1R, FMS
Target/Specificity:
This CSF1R Monoclonal antibody was raised using purified His-tagged recombinant human CSF1R.
Antigen Type: Recombinant Protein
Gene Name: CSF1R
Gene ID: 1436
Primary Accession: P07333
NCBI Accession: NP_005202.2
Other Accession: NP_005202.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq].
Other Names:
Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, CD115, CSF1R, FMS
Target/Specificity:
This CSF1R Monoclonal antibody was raised using purified His-tagged recombinant human CSF1R.
Antigen Type: Recombinant Protein
Gene Name: CSF1R
Gene ID: 1436
Primary Accession: P07333
NCBI Accession: NP_005202.2
Other Accession: NP_005202.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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