CSH1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP10929b
Catalog Number: AC-AP10929b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30083
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30083
Applications: WB, IHC-P
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq].
Other Names:
CSH1; Chorionic somatomammotropin hormone; Lactogen; Placental lactogen
Target/Specificity:
This CSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-204 amino acids from the C-terminal region of human CSH1.
Antigen Region:
177-204
Antigen Type: Synthetic Peptide
Primary Accession: P01243
NCBI Accession: NP_001308.1;NP_066271.1
Other Accession: P01241; P01242; Q14406; P0DML3; P0DML2; NP_001308.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq].
Other Names:
CSH1; Chorionic somatomammotropin hormone; Lactogen; Placental lactogen
Target/Specificity:
This CSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-204 amino acids from the C-terminal region of human CSH1.
Antigen Region:
177-204
Antigen Type: Synthetic Peptide
Primary Accession: P01243
NCBI Accession: NP_001308.1;NP_066271.1
Other Accession: P01241; P01242; Q14406; P0DML3; P0DML2; NP_001308.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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