Csk (phospho-S364) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4673
Background:
C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).
Alternative Name:
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK
Application Dilution: WB: 1:500~1:1000
Specificity: p-Csk (S364) polyclonal antibody detects endogenous levels of Csk protein when phosphorylated at Ser364.
Immunogen:
Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364.
MW: ~ 50 kDa
Swis Prot.: P41240
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).
Alternative Name:
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK
Application Dilution: WB: 1:500~1:1000
Specificity: p-Csk (S364) polyclonal antibody detects endogenous levels of Csk protein when phosphorylated at Ser364.
Immunogen:
Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364.
MW: ~ 50 kDa
Swis Prot.: P41240
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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