CSNK2A2 polyclonal, anti-human, mouse, rat

Background:
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase I, I, I and Ie, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an 2∫2 or an '∫2 structure. The a catalytic subunit is stimulated by the ∫ regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Synonyms: CK2A2, CK2alpha', CSNK2A1

Cellular Location: Cytosol Nucleus Plasma Membrane

Immunogen:
Recombinant protein of human CSNK2A2

Gene Symbol: CSNK2A2

Gene ID: 1459

Swiss prot: P19784

Calculated MW: 41kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.