CSRP3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6950
Background:
Cysteine and glycine-rich protein 3 (CRP3), also known as cysteine-rich protein 3, CLP (cardiac LIM protein), MLP (muscle LIM protein), LMO4 or CMD1M, is an essential nuclear regulator of myogenic differentiation. CRP3 contains two LIM zinc-binding domains linked to short glycine-rich repeats and a potential nuclear localization signal. CRP3 is present in differentiated heart during early development and in a subset of other striated muscles during later stages. Defects in the gene encoding CRP3 (CSRP3) can cause dilated cardiomyopathy 1M (CMD1M), a disease characterized by reduced systolic functionand cardiac dilation. Human CSRP3 maps to the gene locus 11p15.1.
Alternative Name:
Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein, CSRP3, CLP, MLP
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CSRP3 polyclonal antibody detects endogenous levels of CSRP3 protein.
Immunogen:
Recombinant full length Human CSRP3.
MW: ~ 21 kDa
Swis Prot.: P50461
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cysteine and glycine-rich protein 3 (CRP3), also known as cysteine-rich protein 3, CLP (cardiac LIM protein), MLP (muscle LIM protein), LMO4 or CMD1M, is an essential nuclear regulator of myogenic differentiation. CRP3 contains two LIM zinc-binding domains linked to short glycine-rich repeats and a potential nuclear localization signal. CRP3 is present in differentiated heart during early development and in a subset of other striated muscles during later stages. Defects in the gene encoding CRP3 (CSRP3) can cause dilated cardiomyopathy 1M (CMD1M), a disease characterized by reduced systolic functionand cardiac dilation. Human CSRP3 maps to the gene locus 11p15.1.
Alternative Name:
Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, CRP3, LIM domain protein, cardiac, Muscle LIM protein, CSRP3, CLP, MLP
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: CSRP3 polyclonal antibody detects endogenous levels of CSRP3 protein.
Immunogen:
Recombinant full length Human CSRP3.
MW: ~ 21 kDa
Swis Prot.: P50461
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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