CST3 Polyclonal Antibody

Background:
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

Research Area: Tags & Cell Markers, Cell Biology, Stem Cells, Cardiovascular

Synonyms:
AD8, Amyloid angiopathy and cerebral hemorrhage, ARMD11, CST3 protein, Cystatin 3, CystatinC, Epididymis secretory protein Li 2, bA218C14.4, Gamma trace, HCCAA, HEL S 2, Neuroendocrine basic polypeptide, Post gamma globulin

Immunogen: Recombinant Human Cystatin-C protein

Swissprot: P01034
Gene ID: 1471

Calculated MW: 15 kDa
Observed MW: 15 kDa

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Concentration: 1mg/mL
Dilution:
WB 1:2000-1:4000
IHC 1:100-1:300

Storage:
Store at -20℃. Avoid freeze / thaw cycles.