CST8 polyclonal, anti-human, mouse

CST8 polyclonal, anti-human, mouse

€388.00
In stock
SKU
BS6266
Catalog Number: BS6266
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IF

Datasheet
Background:
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are also preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs. Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein that is expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.

Alternative Name:
CRES, CST 8, Cst8, CST8, cystatin 8 (cystatin related epididymal specific), Cystatin 8, Cystatin related epididymal specific, Cystatin related epididymal specific protein, Cystatin related epididymal spermatogenic protein, Cystatin related protein epididymis specific, Cystatin-8, Cystatin-related epididymal spermatogenic protein,

Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200

Specificity: CST8 polyclonal antibody detects endogenous levels of CST8 protein.

Immunogen:
Recombinant full length Human CST8.

MW: ~ 16 kDa

Swis Prot.: O60676

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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