CSTB Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14355c
Background:
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and kininogens. This gene encodes astefin that functions as an intracellular thiol protease inhibitor.The protein is able to form a dimer stabilized by noncovalentforces, inhibiting papain and cathepsins l, h and b. The protein isthought to play a role in protecting against the proteases leakingfrom lysosomes. Evidence indicates that mutations in this gene areresponsible for the primary defects in patients with progressivemyoclonic epilepsy (EPM1).
Other Names:
Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Gene Name: CSTB
Gene ID: 1476
Primary Accession: P04080
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and kininogens. This gene encodes astefin that functions as an intracellular thiol protease inhibitor.The protein is able to form a dimer stabilized by noncovalentforces, inhibiting papain and cathepsins l, h and b. The protein isthought to play a role in protecting against the proteases leakingfrom lysosomes. Evidence indicates that mutations in this gene areresponsible for the primary defects in patients with progressivemyoclonic epilepsy (EPM1).
Other Names:
Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Gene Name: CSTB
Gene ID: 1476
Primary Accession: P04080
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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