CSTB polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP14355c
Catalog Number: AC-AP14355c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34048
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34048
Applications: WB
Datasheet
Request Information
Background:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Other Names:
Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Target/Specificity:
This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.
Antigen Region:
10-39
Antigen Type: Synthetic Peptide
Gene Name: CSTB
Gene ID: 1476
Primary Accession: P04080
NCBI Accession: NP_000091.1
Other Accession: P35478; P25417; NP_000091.1; Q10994
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).
Other Names:
Cystatin-B, CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB, CST6, STFB
Target/Specificity:
This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.
Antigen Region:
10-39
Antigen Type: Synthetic Peptide
Gene Name: CSTB
Gene ID: 1476
Primary Accession: P04080
NCBI Accession: NP_000091.1
Other Accession: P35478; P25417; NP_000091.1; Q10994
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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