CtBP1/2 (Phospho Ser158/164) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Research Area: Cancer, Cell biology, Epigenetics and nuclear signaling, Microbiology

Synonyms: CtBP1/2 , Phospho Ser158/164, C-terminal-binding protein 1, CtBP1, EC 1.1.1.-

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year