CTCFL polyclonal, anti-human, mouse, rat

Background:
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: BORIS, CT27, CTCF-T, HMGB1L1, dJ579F20.2

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human CTCFL

Gene Symbol: CTCFL

Gene ID: 140690

Swiss prot: Q8NI51

Calculated MW: 76kDa

Recommended dilution:
WB 1:500-2000, IF 1:20-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.