CTDP1 Polyclonal Antibody

Background:
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Synonyms:
CCFDN, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1, CTD of POLR2A, phosphatase of, subunit 1, CTDP1, CTDP1, EC 3.1.3.16 , RNA polymerase II subunit A C terminal domain phosphatase, RNA polymerase II subunit A C-terminal domain phosphatase, Serine phosphatase FCP1a, TFIIF associating CTD phosphatase , TFIIF-associating CTD phosphatase 1 , TFIIF-associating CTD phosphatase, Transcription factor IIF-associating CTD phosphatase 1

Immunogen: Synthetic peptide of human CTDP1

Swissprot: Q9Y5B0
Gene Accession: NP004706

Calculated MW: 104 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.56 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.