CTDSPL polyclonal, anti-human, mouse, rat

Background:
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.

Alternative Name:
CTDSP-like, NLI-interacting factor 1, hYA22, SCP3, Small CTD phosphatase 3, CTDSPL, C3orf8, NIF1, NIFL, SCP3, YA22, C3orf8, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, CTD small phosphatase-like protein, CTDSL, CTDSP-like, Ctdspl, hYA22, N-like protein, NIF-like protein, NLI-interacting factor 1, Nuclear LIM interactor-interacting factor 1, Protein YA22, RB protein serine phosphatase from chromosome 3, RBSP3, SCP3, Small C-terminal domain phosphatase 3, Small CTD phosphatase 3,

Application Dilution:
WB:1:500
FC:1:50-1:100

Specificity: CTDSPL polyclonal antibody detects endogenous levels of CTDSPL protein.

Immunogen:
Recombinant protein within human CTDSPL aa 50-300.

MW: 31kDa

Swiss-Prot: O15194(Human) P58465(Mouse) Unigene: 37030(Rat)

Purification & Purity:
Protein affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.