CTGF polyclonal, anti-human, rat

Quantity: 100 µg

Background:
CTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. And the encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis.

Description:
Rabbit IgG polyclonal antibody for Connective tissue growth factor (CTGF) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
CCN 2 antibody, CCN family member 2 antibody, CCN2 antibody, Connective Tissue Growth Factor antibody, CTGF antibody, CTGF_HUMAN antibody, Hcs 24 antibody, Hcs24 antibody, Hypertrophic chondrocyte specific protein 24 antibody, Hypertrophic chondrocyte-specific gene product 24 antibody, Hypertrophic chondrocyte-specific protein 24 antibody, IBP-8 antibody, IGF-binding protein 8 antibody, IGFBP-8 antibody, IGFBP8 antibody, Insulin like Growth Factor Binding Protein 8 antibody, Insulin-like Growth Factor-Binding Protein 8 antibody, MGC102839 antibody, NOV 2 antibody, NOV2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.E.coli-derived human CTGF recombinant protein (Position: R58-A349). Human CTGF shares 95.5% and 95.9% amino acid (aa) sequence identity with mouse and rat CTGF, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.