CTNL1 polyclonal antibody, anti-human, mouse

Background:
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).,induction:Down-regulated in cancer pancreatic cells undergoing differentiation and apoptosis.,Belongs to the vinculin/alpha-catenin family.,subunit:Interacts with ARHGEF1.,tissue specificity:Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland.,

Research Area: Signal transduction

Synonyms: Alpha-catulin , Alpha-catenin-related protein, ACRP, Catenin alpha-like protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year