CTNNA1 Polyclonal Antibody

Background:
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

Research Area: Cancer, Signal Transduction, Stem Cells

Synonyms:
CAP102, MDPT2, Catenin alpha 1, CTNNA1

Immunogen: Recombinant fusion protein of human CTNNA1 (NP_001894.2).

Swissprot: P35221
Gene ID: 1495

Calculated MW: 59 kDa/100 kDa/102 kDa
Observed MW: 115 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.