CTNNB1 polyclonal(C-term), anti-human
€0.00
In stock
SKU
AC-AP19562b
Catalog Number: AC-AP19562b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41158
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41158
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Other Names:
Catenin beta-1, Beta-catenin, CTNNB1, CTNNB
Target/Specificity:
This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-751 amino acids from the C-terminal region of human CTNNB1.
Antigen Region:
723-751
Antigen Type: Synthetic Peptide
Gene Name: CTNNB1 (HGNC:2514)
Gene ID: 1499
Primary Accession: P35222
NCBI Accession: NP_001091679.1;NP_001091680.1;NP_001895.1
Other Accession: Q9WU82; Q02248; Q0VCX4; NP_001091679.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Other Names:
Catenin beta-1, Beta-catenin, CTNNB1, CTNNB
Target/Specificity:
This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-751 amino acids from the C-terminal region of human CTNNB1.
Antigen Region:
723-751
Antigen Type: Synthetic Peptide
Gene Name: CTNNB1 (HGNC:2514)
Gene ID: 1499
Primary Accession: P35222
NCBI Accession: NP_001091679.1;NP_001091680.1;NP_001895.1
Other Accession: Q9WU82; Q02248; Q0VCX4; NP_001091679.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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