CTNS polyclonal, anti-human, mouse, rat

Background:
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Alternative Name:
Cystinosin

Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200

Specificity: CTNS polyclonal antibody detects endogenous levels of CTNS protein.

Immunogen:
Recombinant full length Human CTNS.

MW: ~ 41kDa

Swis Prot.: O60931

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.