CTNS polyclonal(C-term), anti-human

Background:
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Other Names:
Cystinosin, CTNS

Target/Specificity:
This CTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the C-terminal region of human CTNS.

Antigen Region:
341-367

Antigen Type: Synthetic Peptide

Gene Name: CTNS {ECO:0000303|PubMed:9537412, ECO:0000312|HGNC:HGNC:2518}
Gene ID: 1497
Primary Accession: O60931
NCBI Accession: NP_001026851.2;NP_004928.2
Other Accession: NP_004928.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.