CTPS rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],catalytic activity:ATP + UTP + NH(3) = ADP + phosphate + CTP.,enzyme regulation:Activated by GTP and inhibited by CTP.,function:Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.,pathway:Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.,similarity:Belongs to the CTP synthase family.,similarity:Contains 1 glutamine amidotransferase type-1 domain.,

Synonyms: CTPS1, CTPS, CTP synthase 1, CTP synthetase 1, UTP--ammonia ligase 1

Gene Name: CTPS1

Gene ID: 1503

SwissProt ID: P17812

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.